You are a collection of over 30 trillion human cells.
Every one of these cells, those in your brain, lungs, liver, skin, and everywhere else, derives from a single pluripotent type of cell called a stem cell.
This blog is about how stem cells are going to change medicine forever, extend life, and potentially save your life in the years ahead.
In this blog we’ll talk about why it’s important to bank the cells of your newborn children or grandchildren – and potentially your own (no matter how old you are).
In a recent Abundance 360 webinar, I had the chance to interview Dr. Robert (Bob) Hariri, one of the world’s foremost experts on stem cells. He’s the Founder, Chairman and Chief Science Officer of Celgene Therapeutics, and the Co-founder and Vice-Chairman of Human Longevity Inc. (HLI). Here is what we discussed.
Stem cells have the remarkable ability to “differentiate” into any other type of cell in the body.
Dr. Hariri explains, “At the beginning of life, a single nondescript cell with a giant nucleus, cytoplasm, and a cell membrane, goes on to replicate and create every cell in our body.
"This single cell contains within it the entire genetic code – the biological software – necessary to produce everything that ultimately defines each and every specialized cell type in the body.”
After our body has developed, among our tens of trillions of fully differentiated human cells (skin, heart, muscle, kidney) remain a population of quiescent stem cells waiting to be called into action to help repair damaged tissue. These stem cells reside everywhere: in our bone marrow, in our fat, and in every single tissue compartment.
And, as Dr. Hariri describes them, “they are nature’s perfect repair kit – ready to be mobilized and facilitate repair when needed.”
If we have the ability to constantly repair ourselves, what goes wrong?
Why do we age?
Current theory says two things:
First, we deplete our reserves of stem cells during the course of our lives.
Second, our stem cells undergo various ‘epigenetic’ changes (insertions, deletions, mutations) over the course of life, making them less accurate and less adaptable.
Basically, the repairmen of our body die off and go senile.
Normally during our youth, when we experience damage, stem cells are mobilized to the site of damage to effect repair. However, as mentioned above, this capability slows with aging.
But what if you could supplement or rejuvenate your supply of stem cells?
Today, in various locations around the world, researchers and physicians inject stem cells into areas of damage, and explore stem cell therapeutics around heart disease, brain disease, diabetes, cancer treatment, arthritis, spinal cord injuries, burns, macular degeneration, and much more.
The implications of this are staggering.
Of course, the challenge is getting the stem cells to inject in the first place. So where might they come from?
“At your moment of birth, you are probably at the point of biological perfection. Your system hasn’t been exposed to all of those injurious stimuli, like electromagnetic radiation, chemicals, etc., and your biological software is uncorrupted.”
What if we could capture stem cells with our original, uncorrupted DNA at birth and then replicate them into a large number of future dosages and then freeze those doses, making them available for future injection to facilitate repair over the course of our lives?
This is one of the primary concepts that Hariri has been pioneering for some time.
Hariri discovered that in addition to cord blood (the blood found in the umbilical cord of a newborn), the placenta of a newborn is an organ very rich in stem cells.
And rather than discard the leftovers of birth, placentas, if saved, may hold the key to a longer and healthier life.
Hariri created a business called LifeBank USA, which provides private cell banking (FYI, this is where we banked our children’s stem cells).
Lifebank (now part of Celegene Cellular Therapeutics) isolates, processes and cryopreserves cells (putting into a deep freeze, about minus 180 degrees Celsius), keeping them in suspended animation at the most pristine state of their existence.
There’s no question about the promise of stem cells, the question is how you rejuvenate the reparative engine of your body.
This is one of the key areas of research at Human Longevity Inc.
In principle, there are three approaches:
As humans, we’ve just come to accept the notion that we are going to die.
One hundred years ago, we accepted that most people live to age 50 or 60.
A decade ago, if you made it to 75 or 80, good for you…
Today, if you’re in your 30’s, 40’s or 50’s (maybe even 60’s), you have the chance to make it to 100.
This decade we will begin to develop the tools to understand how to extend the healthy human lifespan, and stem cells will be one key to help us get there.
This is the sort of conversation we discuss at my 250-person executive mastermind group called Abundance 360. The program is highly selective and we’re almost full, looking for a few last CEOs and entrepreneurs who want to change the world. You can apply here.
Share this with your friends, especially if they are interested in any of the areas outlined above.
P.S. Every weekend I send out a “Tech Blog” like this one. If you want to sign up, go to PeterDiamandis.com and sign up for this and my Abundance blogs.
P.P.S. I’ve just released a podcast with my dear friend Dan Sullivan called Exponential Wisdom. Our conversations focus on the exponential technologies creating abundance, the human-technology collaboration, and entrepreneurship. Head here to listen and subscribe: a360.com/podcast