Moonshots with Peter Diamandis

EP #251 David Sinclair: The GLP-1 Side Effect No One Talks About, What AI Found in His Lab, and Reversing Blindness | Q&A

Written by Peter H. Diamandis | Apr 28, 2026 7:00:00 AM

This episode was filmed at the 2026 Abundance360 Summit. Learn more at https://www.abundance360.com/

This Q&A is about longevity, and especially how David Sinclair sees AI speeding up drug discovery, biological-age reversal, and the future of healthspan. It also covers GLP-1s, telomeres, genetics, muscle preservation, hormone replacement, indoor environment, and the role of mindset in aging well.

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Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360

David A. Sinclair, A.O., Ph.D., is a tenured Professor of Genetics at Harvard Medical School and a serial biotech entrepreneur. Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360

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