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EP #78 The Groundbreaking Science of Water Fasting w/ Valter Longo


In this episode, Peter and Valter discuss the principles of the fasting-mimicking diet, which involves a 5-day period of reduced caloric intake to impact various diseases and potentially extend lifespan positively. The episode delves into the science and practice of dieting, intermittent fasting, and the importance of what, how, and how much to eat for optimal health and longevity.


  • 19:17 | Fasting's Autophagy Effects
  • 27:55 | Benefits of Water Fasting
  • 56:20 | The Five Pillars of Longevity

Valter D. Longo, an Italian-American biogerontologist and cell biologist, is a prominent figure in the field of longevity, dedicated to eradicating age-related diseases and educating people on living a healthy life. Known for his groundbreaking research on fasting and nutrient response genes, Longo's work focuses on their impact on cellular protection, aging, and diseases. He currently serves as a professor at the USC Davis School of Gerontology and as the director of the USC Longevity Institute.

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