12 min read

the next data-driven Healthtech Revolution

By Peter H. Diamandis on Jul 5, 2020

Increasing your healthspan (i.e. making 100 years old the new 60) will depend to a large degree on artificial intelligence.

Topics: Abundance Data Sensors AI Medicine/Health Longevity health healthcare mobile health preventive medicine digital devices aging mHealth
20 min read

The Three R’s of Regenerative Medicine

By Peter H. Diamandis on Jun 28, 2020

Lizards can regrow entire limbs. Flatworms, starfish, and sea cucumbers regrow entire bodies.

Topics: 3D Printing Medicine/Health Longevity health healthcare bio-printing biotech Stem Cells entrepreneur regenerative medicine vitality
8 min read

Longevity & Vitality - A Renaissance of Drugs and Genomics

By Peter H. Diamandis on Jun 21, 2020

The causes of aging are extremely complex and unclear.

Topics: Abundance AI Medicine/Health Longevity health healthcare preventive medicine Stem Cells protein-folding aging
6 min read

why we age....

By Peter H. Diamandis on Jun 14, 2020

Healthcare today is reactive, retrospective, bureaucratic and expensive. It's sick care, not healthcare.

Topics: Abundance AI Medicine/Health Longevity health healthcare preventive medicine Stem Cells protein-folding aging
11 min read

Longevity & Vitality - Part 5: The Three R’s of Regenerative Medicine

By Peter H. Diamandis on Mar 24, 2019

Lizards can regrow entire limbs. Flatworms, starfish, and sea cucumbers regrow entire bodies.

Topics: 3D Printing Medicine/Health Longevity health healthcare bio-printing biotech Stem Cells entrepreneur regenerative medicine vitality
10 min read

Longevity & Vitality Part 4: The Next Data-Driven Healthtech Revolution

By Peter H. Diamandis on Feb 17, 2019

Increasing your healthspan (i.e. making 100 years old the new 60) will depend to a large degree on artificial intelligence.

Topics: Abundance Data Sensors AI Medicine/Health Longevity health healthcare mobile health preventive medicine digital devices aging mHealth
7 min read

Longevity & Vitality Part 3: AI Augments Healthcare and Longevity

By Peter H. Diamandis on Feb 10, 2019

When it comes to the future of healthcare, perhaps the only technology more powerful than CRISPR is Artificial Intelligence.

Topics: Abundance AI Medicine/Health Longevity health healthcare preventive medicine Stem Cells protein-folding aging
8 min read

Longevity & Vitality Part 2: A Renaissance of Drugs and Genomics

By Peter H. Diamandis on Jan 20, 2019

The causes of aging are extremely complex and unclear.

Topics: Abundance AI Medicine/Health Longevity health healthcare preventive medicine Stem Cells protein-folding aging
6 min read

longevity & vitality part 1 - why we age....

By Peter H. Diamandis on Jan 13, 2019

Healthcare today is reactive, retrospective, bureaucratic and expensive. It's sick care, not healthcare.

Topics: Abundance AI Medicine/Health Longevity health healthcare preventive medicine Stem Cells protein-folding aging
6 min read

The Next Hundred-Billion-Dollar Opportunity

By Peter H. Diamandis on Jan 11, 2019

What can a Human do, that can’t be replicated by AI? 

Topics: AI Medicine/Health Deepmind Artificial Intellegence crowd the crowd wisdom of the crowd protein-folding crowdsourcing AlphaFold generative adversarial networks GANs
10 min read

Abundance Insider: January 4th, 2019

By Peter H. Diamandis on Jan 4, 2019

In this week's Abundance Insider: 3D-printed rib replacements, gesture-directed gadgets, and a new weapon in the fight against Alzheimer’s.

Cheers,
Peter, Marissa, Kelley, Greg, Bri, Jarom, Joseph, Derek, Jason, Claire and Max

P.S. Send any tips to our team by clicking here, and send your friends and family to this link to subscribe to Abundance Insider.

P.P.S. Want to learn more about exponential technologies and hone in on your MTP/ Moonshot? Abundance Digital includes 100+ hours of course work and video archives for entrepreneurs, like you. Keep up to date on exponential news and get feedback on your boldest ideas from an experienced, supportive community. Click here to learn more and sign up.

FCC Clears Google To Pursue “Minority Report”-Like Gesture System

What it is: The FCC recently granted permission for Google to continue development of Project Soli, its radar-based gesture tracking system. Launched in 2015, Soli promised to change the way we interact with our devices, enabling users to push buttons, turn dials, or zoom in and out without physically touching them. To improve tracking accuracy and reliability, Google needed to increase the radar’s power, which led to a protracted discussion with the FCC and striking an agreement with Facebook on interference concerns. With this decision, Google is again free to improve on its already slim 10 mm x 8 mm hardware package, associated software and machine learning algorithms.

Why it's important: WIth a small design and low power consumption, the Soli is well-suited to embed in wearables, phones, PC’s, cars, and IoT devices to name just a few. Additionally, as Soli opens up to a broader community with its SDK, look for additional gestures and use cases to arrive, such as in AR and VR environments.  Share on Facebook

Spotted by Marissa Brassfield / Written by Jason Goodwin 

Drinkable Cocktail Stymies Alzheimer’s Disease At Its Start

What it is: A first step in the onset of Alzheimer’s occurs when amyloid beta peptides bind to prion proteins in the brain’s neurons. After testing tens of thousands of different molecules, researchers at Yale University identified a mixture of small polymer molecules that can inhibit this amyloid beta to prior binding mechanisms. The polymer mixture inhibits this preliminary Alzheimer’s mechanism, and the researchers also discovered that administering the molecules repaired memory function in mice engineered to display Alzheimer’s. The next step before clinical trials is to ensure that the cocktail is safe for humans.

Why it's important: Neurodegenerative diseases are among the leading causes of decreased health and longevity. While we often hear of regenerative medicine (stem cells, 3d printing, and prosthetics) augmenting our physical health, ensuring the longevity of our minds is crucial to extending the human health span. More than ever, an abundance of research and technology development (from biochemistry like in this study to nanotechnology to artificial intelligence) is directly working to combat Alzheimer’s.  Share on Facebook

Spotted by Marissa Brassfield / Written by Max Goldberg 

Patient Receives 3D-Printed Rib Implant In Breakthrough Procedure

What it is: 2018 was a big year in 3D printing, particularly in medicine. Case in point is the 3D-printed rib that Ivaylo Josifov received in Bulgaria last month. After doctors found an abnormality in a rib bone that might lead to pulmonary complications, they decided to replace the rib. Enter 3DGence and 3dbgprint, two startups pushing the limits of 3D printing and modeling. After scanning Ivaylo’s existing rib, the team iterated on the design to ensure an exact match in shape, flexibility and sturdiness and sent it to 3DGence for printing in a semi-rigid polyamide capable of withstanding the heat, ethylene oxide and radiation necessary for sanitization. A day later — and at a fraction of the cost to create a similar rib from titanium — the rib was ready for implantation.

Why it's important: Josifov’s rib is impressive for many reasons, but perhaps most interesting is the use of FDM — Fused Deposition Modeling — which is essentially the same technology in every Makerbot sitting in your garage or Maker Space. Maybe you won’t do your own bone replacements, but look for the democratization of design and manufacturing to continue, leading to a vast set of new use cases.  Share on Facebook

Spotted by Marissa Brassfield / Written by Jason Goodwin 

This Clever AI Hid Data From Its Creators To Cheat At Its Appointed Task

What it is: Striving to perfect Google Maps’ aerial-to-Street View translation, Google and Stanford AI researchers discovered they had been cleverly deceived by their own machine learning agent, CycleGAN. Image-to-image translation requires a program to transform images of one type into another class of image. In Google’s case, this means converting satellite imagery into street maps, and vice versa. However, whereas CycleGAN was intended to interpret aerial view features and generate a corresponding street map, the agent created its own shortcut instead. Encoding hidden data in its translations, the agent found it could then easily reconstruct original source images without generating aerial views from scratch.

Why it's important: This impressive act of subterfuge demonstrates several key takeaways regarding neural network-based programs. Principally: computers will do exactly what you tell them to do. As a result, an ML agent might even find ways to transmit information to itself, imperceptible to the human eye, in the interest of solving a problem more easily and efficiently. This doesn’t mean AIs are outmaneuvering us per se, but rather that AI scientists need robust measures to validate AI output at each stage of a program's process. Only then can we ensure that neural networks solve problems in the ways we intend them to do so.  Share on Facebook

Spotted by Marissa Brassfield / Written by Claire Adair 

What is Abundance Insider?

This email is a briefing of the week's most compelling, abundance-enabling tech developments, curated by Marissa Brassfield in preparation for Abundance 360. Read more about A360 below.

Want more conversations like this?

At Abundance 360, Peter's 360-person executive mastermind, we teach the metatrends, implications and unfair advantages for entrepreneurs enabled by breakthroughs like those featured above. We're looking for CEOs and entrepreneurs who want to change the world. The program is highly selective. If you'd like to be considered, apply here

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Topics: Abundance Insider 3D Printing Medicine/Health Longevity health healthcare biotech
2 min read

Join Me at Exponential Medicine

By Peter H. Diamandis on Oct 21, 2018

The convergence of exponential technologies including machine learning, artificial intelligence, robotics, networks, sensors, synthetic biology and quantum computing is transforming healthcare.

Topics: Sensors AI Medicine/Health health Artificial Intellegence healthcare preventive medicine personalized medicine IoT industry internet of things digitization
8 min read

Revolutionizing Healthcare

By Peter H. Diamandis on Jul 1, 2018

We are on the brink of a revolution in healthcare.

Topics: AR/VR Medicine/Health Artificial Intellegence healthcare microbiome mobile health preventive medicine personalized medicine
7 min read

Future of AI & Longevity

By Peter H. Diamandis on Jun 17, 2018

What if we could generate novel molecules to target any disease, overnight, ready for clinical trials?

Topics: AI Medicine/Health Longevity machine learning Insilico
8 min read

Optimizing your microbiome

By Peter H. Diamandis on Apr 16, 2018

One of my missions is to extend the healthy human lifespan. 

My brilliant friend Naveen Jain, CEO of Viome, shares this mission and has found some fascinating links between your microbiome and your health.

Your microbiome is mostly located in your gut and contains trillions of microbes. A healthy microbiome is part best friend, part power converter, part engine, and part pharmacy.

If you want to optimize your health, heal chronic disease, or know which foods are right for you… understanding your microbiome is your first step.

At-home test kits, like those offered by Viome, help start the data-gathering process.

From there, Viome uses a technique called meta-transcriptome sequencing to identify all microorganisms living in your gut, from bacteria and viruses to fungi, yeast, parasites and bacteriophages. With this data, Viome recommends personalized foods and supplements to optimize your microbial function.

Here are 10 surprising discoveries about the microbiome that Viome has uncovered... And if you’d like to try Viome (like I have), use this link to get $50 off: viome.com/ABUNDANCE

1. “Healthy” Food Isn’t Always Healthy

You might have been advised to eat your greens, and that greens and nuts are anti-inflammatory. The data show this isn’t always true. 

Spinach, bran, rhubarb, beets, nuts and nut butters all contain Oxalate. We now know that Oxalate-containing food can be harmful, unless you have the microbes present that can metabolize it into a non-harmful substance.

30% of Viome customers lack the microbes to metabolize oxalates properly. In other words, “healthy foods” like spinach are actually not healthy for these people.

Looks like not everyone should follow Popeye’s food plan.

2. “Antioxidants” Aren’t Always Good for Everyone

Like Oxalates, Polyphenols in foods are usually considered very healthy, but unless you have the appropriate microbes that use specific polyphenols, you may not get the full benefit.

One example is a substance found in these foods called ellagic acid. Viome can detect whether your microbiome is metabolizing ellagic acid and converting it into urolithin A. Only the urolithin A has anti-inflammatory and antioxidant effects. Without the microbes to do this conversion, you will not benefit from the ellagic acid in foods.

Nuts, walnuts, raspberries, pomegranate, blackberries, pecans and cranberries all contain Ellagic acid.

After analyzing tens of thousands of people, Viome reports that only about 50% of them benefit from eating more foods containing ellagic acid.

3. Are You Eating Too Much Protein?

When you think high-protein diet… you might think about Paleo, Keto and high-performance diets.

Protein helps build muscle and provide energy, but if you eat too much, it can cause inflammation and decrease longevity.

Viome analyzes the activity of your microbiome to determine whether you are eating too much protein that feeds protein-fermenting bacteria like Alistipes putredinis and Tanneralla forsythia, and if these organisms are producing harmful substances such as ammonia, hydrogen sulfide, p-cresol, or putrescine. These substances can damage your gut lining and lead to conditions like leaky gut.

4. Can “Healthy Foods” Cause Heart Disease?

Choline in certain foods can get converted by bacteria into trimethylamine (TMA), which is associated with heart disease when it gets absorbed into your body and converted to TMAO.

However, TMA conversion doesn’t happen in individuals unless they have the appropriate bacteria in their microbiome.

Viome can see the TMA production pathways, and many of the gammaproteobacteria that do this conversion.

What foods contain choline? Liver, salmon, chickpeas, split peas, eggs, navy beans, peanuts are a small sample.

Before you decide to go full-on pescatarian or paleo, you may want to check if your microbiome is producing TMA with that salmon or steak.

5. Too Much Iron Can Cause Inflammation

Minerals like iron in your food can, in certain inflammatory microbial environments, promote growth of pathogens like Esherichia, Shigella, and Salmonella. Maybe it wasn’t just that raw chicken that gave you food poisoning, but your toxic microbiome that made you sick.

On the other hand, when you don’t have enough iron, you could become anemic, leading to weakness and shortness of breath.

When thinking about how much iron is right for you, look at the data. 

6. Stress and Anxiety Appear in Your Microbiome

Our gut and brain are connected via the vagus nerve. A large majority of neurotransmitters are either produced or consumed by our microbiome. Surprisingly, 90% of all serotonin (a feel-good neurotransmitter) is produced by your gut microbiome, not by your brain.

When you have a toxic microbiome that’s producing a large amount of toxins like hydrogen sulfide, the lining of your gut starts to deteriorate into what’s known as leaky gut.

Think of leaky gut as your gut not having healthy borders or boundaries. When this happens, all kinds of diseases can emerge. When the barrier of the gut breaks down, it starts a chain reaction, causing low-grade chronic inflammation — which has been identified as a potential source of depression and higher levels of anxiety, in addition to many other chronic diseases.

To get the most out of your meditation and truly reduce your stress levels, ensure your diet promotes a healthy microbiome.

7. Your Microbiome Affects Your Energy

If you want more energy, get your microbiome back into balance.

Your microbiome is responsible for calorie extraction, or creating energy, through pathways such as the Tricarboxylic acid cycle. Our bodies depend on the energy that our microbiome produces.

How much energy we get from our food is dependent on how efficient our microbiome is at converting the food into energy. High-performing microbiomes are excellent at converting food into energy -- great for athletes who need extra energy, but suboptimal for those with sedentary lifestyles. And if the microbes can’t or won’t metabolize the glucose (sugar) that you eat, it will be stored as fat.

8. Got Joint Pain? Your Microbiome Can Tell You Why

Lipopolysaccharide (LPS) is a key pro-inflammatory molecule made by some of your microbes. If your microbes are making too much LPS, it can wreak havoc on your immune system and put it into overdrive. When your immune system goes on the warpath, your joints and other body parts often suffer collateral damage.

Perhaps balancing your microbiome is a better solution than reaching for the glucosamine.

Consider your microbiome as the top general of your immune army. It puts your immune system through basic training and determines when it goes to war. 

Ideally, your immune system wins the quick battle and gets some rest, but if your microbiome keeps it on constant high alert, the long, drawn-out war can result in chronic inflammation and chronic diseases. 

Are you really getting older, or is your microbiome just making you feel older because it keeps giving warnings to your immune system, ultimately leading to chronic pain?

If you have any condition ending in “-itis,” it’s possible that when you balance your microbiome, the inflammation from your “-itis” will be reduced.

9. The Link Between Low Stomach Acid and Chronic Disease

The acid in your stomach protects you from the bacteria in your mouth and the parasites and fungi in your food.

When you have low stomach acid, bacteria from your mouth bacteria makes it down to your GI tract. This invasion is associated with, and a risk factor for, autoimmune disease and inflammation in the gut. 

We’re beginning to learn that low stomach acid is perhaps one of the major causes of chronic disease.

What kinds of things cause low stomach acid? Stress and antacids like Nexium, Zantac and Prilosec.

10. Carbs Can Be Protein Precursors 

As long as your microbiome is up to the task, carbs aren’t as bad as you might think.

The key is whether your microbiome can transform the starches you eat into amino acids.

Our microbiome comprises 20% of our Branch Chain Amino Acids (BCAA’s), and it will adapt to make these vital BCAAs for us in almost any way it can.

Essentially, your microbiome is hooking up carbons and hydrogens into different formulations of BCAA’s, depending on what you feed it. The microbiome is excellent at adapting and pivoting based on your diet and environment.

Get Data on Your Microbiome Health

Given the research emerging daily about the microbiome and its importance on your quality of life, prioritizing the health of your microbiome is essential.

When you have a healthy microbiome, you’ll have a healthier life.

Viome is the only company with the technology to help you identify what your microbiome is actually doing. The combination of Viome’s metatranscriptomic technology and cutting-edge artificial intelligence enables you to manage your microbiome health.

I hope you try Viome to figure out what foods work best for you. To get $50 off an annual at-home test kit from Viome, head here: viome.com/ABUNDANCE

Join Me

1. A360 Executive Mastermind: This is the sort of conversation I explore at my Executive Mastermind group called Abundance 360. The program is highly selective, for 360 abundance and exponentially minded CEOs (running $10M to $10B companies). If you’d like to be considered, apply here.

Share this with your friends, especially if they are interested in any of the areas outlined above.

2. Abundance-Digital Online Community: I’ve also created a Digital/Online community of bold, abundance-minded entrepreneurs called Abundance-Digital.

Abundance-Digital is my ‘onramp’ for exponential entrepreneurs – those who want to get involved and play at a higher level. Click here to learn more.

Topics: Medicine/Health
5 min read

Celularity - Revolutionizing Cellular Medicine

By Peter H. Diamandis on Feb 18, 2018

The field of stem cells (Cellular Medicine) is poised to revolutionize medicine, augmenting our longevity and immunity.

Topics: Medicine/Health Longevity
8 min read

Abundance Insider: December 15, 2017 Edition

By Peter H. Diamandis on Dec 15, 2017

In this week's Abundance Insider: AI masters chess, addiction-fighting smart pills, and data on the $7 trillion autonomous car industry.

Topics: Abundance Insider Transportation AI Medicine/Health
3 min read

3 Amazing Longevity Companies

By Peter H. Diamandis on Sep 25, 2017

Age is the single leading risk factor for virtually every significant disease including cancer, cardiovascular, respiratory, neurological and other degenerative diseases.

Topics: Medicine/Health Longevity